FOUND: Difference between revisions
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== References == | == References == | ||
* Güntert, P., Billeter, M., Ohlenschläger, O., Brown, L | * Güntert, P., Billeter, M., Ohlenschläger, O., Brown, L. & Wüthrich, K. Conformational analysis of protein and nucleic acid fragments with the new grid search algorithm FOUND[http://www.bpc.uni-frankfurt.de/guentert/Intranet/Reprints/Guntert98b.pdf .] [http://dx.doi.org/10.1023/A:1008391403193 J. Biomol. NMR 12, 543–548 (1998)] | ||
Revision as of 16:12, 14 August 2009
Grid search algorithm
FOUND is a grid search algorithm that is capable of performing systematic local conformation analyses for arbitrary contiguous fragments of proteins and nucleic acids. It uses torsion angles as the only degrees of freedom to identify all conformations that fulfill the steric and NMR-derived conformational restraints within a contiguous molecular fragment. The results of the local conformation analysis include allowed torsion angle ranges and stereospecific assignments for diastereotopic substituents, which can be included in the input of a subsequent structure calculation.
FOUND was written by Peter Güntert and Martin Billeter.
Availability
- FOUND is a module of the program CYANA. It is not available as a separate program.
References
- Güntert, P., Billeter, M., Ohlenschläger, O., Brown, L. & Wüthrich, K. Conformational analysis of protein and nucleic acid fragments with the new grid search algorithm FOUND. J. Biomol. NMR 12, 543–548 (1998)